We are a team of health care professionals dedicated and committed to treating patients with brain tumours and improving the overall outcomes and management of the disease burden. We have a vision and pursuit to understand why tumours develop and to create new treatment strategies.
WELCOME TO THE ZADEH LAB WEBSITE
Dr. Gelareh Zadeh is a Professor at the Department of Surgery, University of Toronto, and Head of Neurosurgery at Toronto Western Hospital. She leads Surgical Oncology at Princess Margaret Cancer Center and is a Senior Scientist at Princess Margaret Cancer Research Institute.
She holds the Wilkins Family Chair in Brain Tumor Research focusing on building surgical clinical trials for brain tumor patients.
Internationally, she is the President of the Society for Neuro-Oncology and Editor-in-Chief of Neuro-Oncology Advances, an open access journal of Society of Neuro-Oncology and European Association of Neuro-Oncology.
Her clinical practice focuses on Skull Base Neuro-Oncology, with dedicated general brain tumour clinic and many multidisciplinary clinics that she has established at UHN such as skull base, pituitary, brain metastases, gamma knife, and neurofibromatosis clinic.
Molecular Profiling Can Help Identify the Best Treatment Approaches For Meningiomas
A recent study published highlights the potential of molecular profiling to predict treatment responses in meningiomas, the most common primary brain tumor in adults. The study identified specific molecular biomarkers that can guide treatment decisions, improving outcomes by predicting which patients would benefit from surgery or radiotherapy. The findings suggest that personalized treatment approaches, informed by these biomarkers, could enhance survival rates and reduce tumor recurrence, particularly in aggressive meningiomas.
Read more: UHN Article.
Drs. Gelareh Zadeh and Farshad Nassiri Shares Promising Results
Combination therapy shows survival benefits for recurrent glioblastoma patients, surpassing efficacy threshold despite missing primary endpoint. Further research planned to explore its potential in randomized trials. Read more here
A New International Study from UHN Neurosurgeons Using a Novel Approach to Treating Glioblastoma Shows Great Promise for Patients
Drs. Farshad Nassiri and Gelareh Zadeh published the results of a Phase 1/2 clinical trial in Nature Medicine last week. They investigated a therapy that combines injecting an oncolytic virus, which targets and kills cancer cells, directly into a tumour, using intravenous immunotherapy. They found this novel combination therapy can kill the tumour in select patients, extending their survival. “We are cautiously optimistic about the long-term clinical benefits for patients,” Dr. Zadeh told UHN News. UHN was the only Canadian institution involved in this study and treated the majority of the patients enrolled in the trial. Read UHN News for more and be sure to watch this video exploring how these scientists seek to move the needle for glioblastoma patients.
Nassiri, F., Liu, J., Patil, V. et al. A clinically applicable integrative molecular classification of meningiomas. Nature 597, 119–125 (2021). https://doi.org/10.1038/s41586-021-03850-3
Dr. Gelareh Zadeh discusses groundbreaking brain cancer test
Watch this insightful story via @globalnewsto for a glimpse behind-the-scenes into her world @gelarehzadeh @KBI_UHN @UofTNeuroSurge
A one-day educational webinar on current management strategies and future directions
Dr. Gelareh Zadeh named one of Canada’s Most Influential Women in 2021 Top 25 Women of Influence. The annual award recognizes the extraordinary accomplishments of Canada’s self-identified women and gender-diverse role models.
International Day of Women and Girls in Science Event
Gelareh Zadeh becomes first female chair of neurosurgery at University of Toronto
Gelareh Zadeh speaks about the first time she observed a brain operation the same way one might describe discovering a precious jewel.
The push for more female neurosurgeons CTV Interview
Dr. Gelareh Zadeh, a neurosurgeon-scientist at Toronto Western Hospital and the University Health Network, talks about importance of getting more women involved in neurosurgery.
Happy Holidays from Zadeh Lab!
2020 Lab Secret Santa via Zoom
Wishing you a wonderful holiday. All the best in 2021!
Dr. Gelareh Zadeh will be presenting about the Use of Methylation to Change Brain Tumor Management at KBI Neuroscience Rounds on Thursday, February 11, 2021
